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cyclin a  (Bioss)


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    Bioss cyclin a
    Cyclin A, supplied by Bioss, used in various techniques. Bioz Stars score: 92/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cyclin a/product/Bioss
    Average 92 stars, based on 9 article reviews
    cyclin a - by Bioz Stars, 2026-02
    92/100 stars

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    Galectin-12 regulates the proliferation and differentiation of sebocytes. ( A ) Galectin-12 promotes sebocyte proliferation by upregulating key cell-cycle regulators, including CCNA1 and CDK2. ( B ) Galectin-12 promotes sebocyte differentiation and lipogenesis by upregulating PPARγ, which drives the expression of downstream targets, including ACS2 and DGAT1, that are essential for triglyceride and cholesterol synthesis.

    Journal: Biomolecules

    Article Title: Galectin-12 in the Regulation of Sebocyte Proliferation, Lipid Metabolism, and Immune Responses

    doi: 10.3390/biom15060837

    Figure Lengend Snippet: Galectin-12 regulates the proliferation and differentiation of sebocytes. ( A ) Galectin-12 promotes sebocyte proliferation by upregulating key cell-cycle regulators, including CCNA1 and CDK2. ( B ) Galectin-12 promotes sebocyte differentiation and lipogenesis by upregulating PPARγ, which drives the expression of downstream targets, including ACS2 and DGAT1, that are essential for triglyceride and cholesterol synthesis.

    Article Snippet: Galectin-12 was shown to upregulate the expression of cyclin A1 and CDK2, facilitating the progression of sebocytes through the cell cycle and into the S phase, thereby promoting sustained proliferation [ ].

    Techniques: Expressing